Ultrasound??Promoted Synthesis of 2, 3??Bis (4??hydroxyphenyl) indole Derivatives as Inherently Fluorescent Ligands for the Estrogen Receptor

SD Koulocheri, SA Haroutounian

文献索引：Koulocheri, Sophia D.; Haroutounian, Serkos A. European Journal of Organic Chemistry, 2001 , # 9 p. 1723 - 1729

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被引用次数: 17

摘要

Abstract A series of 2, 3-bis (4-hydroxyphenyl) indole derivatives 4c− f was prepared by ultrasound-promoted intramolecular cyclodehydration of a polyphosphoric acid solution of α- anilinyl-(or 3-anisidyl) desoxyanisoins 2c− f, and their optical spectroscopy and estrogen receptor (ER) binding properties were studied. Compounds 4c− f give intense long- wavelength fluorescent emission, sensitive to solvent polarity and pH. Furthermore, the ...