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Journal of the American Chemical Society

The synthesis and study of certain new derivatives of phenacetin

MT Bogert, WH Taylor

文献索引:Bogert; Taylor Journal of the American Chemical Society, 1927 , vol. 49, p. 1582

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被引用次数: 3

摘要

Salicyl p-phenetidide, C2HjOCsH4NHCOC6H40H, was prepared by Bolezzi3 in 1898 and by Cohn4 in 1900, the former describing also its acetyl (mp, 132') and various other derivatives. However, it was hydrolyzed with difficulty and but little absorbed by the system, for the most part passing through unaltered and hence having no important physiological effect. j In this respect it resembled the behavior of salicylates of certain other antipyretic ...