1, 3-Dipolar cycloaddition route to oxygen heterocyclic triones

RCF Jones, KAM Duller, SIE Vulto

文献索引：Jones, Raymond C. F.; Duller, Kathryn A. M.; Vulto, Simone I. E. Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 3 p. 411 - 416

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被引用次数: 2

摘要

1, 3-Dipolar cycloadditon of nitrile oxides, formed by dehydration of primary nitro compounds, with pyrrolidine enamines of protected γ-hydroxy-β-keto esters affords isoxazole-4-carboxylates; these are subjected to N–O bond cleavage and lactonisation to afford 3-acyltetronic acids and 3-acyl-4-hydroxytetrahydropyra