Electrochemical oxidation of aldehyde-N-arylhydrazones into symmetrical-2, 5-disubstituted-1, 3, 4-oxadiazoles

S Singh, LK Sharma, A Saraswat, IR Siddiqui…

文献索引：Singh, Sushma; Sharma, Laxmi K.; Saraswat, Apoorv; Siddiqui, Ibadur R.; Singh, Rana K. Pal Research on Chemical Intermediates, 2014 , vol. 40, # 3 p. 947 - 960

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被引用次数: 4

摘要

Abstract A convenient, efficient and one-pot synthesis of chemically and pharmaceutically interesting symmetrical-2, 5-disubstituted-1, 3, 4-oxadiazoles is reported. The protocol involves anodic oxidation of aldehyde-N-arylhydrazones in anhyd. MeCN–LiClO 4. Constant potential electrolysis carried out in an undivided cell and platinum electrodes leads to the formation of the corresponding oxadiazoles under ambient condition and the mechanism ...