The Journal of Organic Chemistry

Stereoselective oxidation by thionyl chloride leading to the indeno [1, 2-c] isoquinoline system

M Cushman, L Cheng

文献索引：Cushman,M.; Cheng,L. Journal of Organic Chemistry, 1978 , vol. 43, p. 3781 - 3783

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被引用次数: 76

摘要

In the"-coupled spectra of the 4-alkylisoquinolines, the resonances of C-6 and C-7 were predictably observed as clean doublets of doublets and that of C-8 appeared as a doublet of multiplets. It was thus possible to easily differentiate the C-7 and C-8 resonances, thereby completing the chemical shift assignments of the 4-substituted isoquinolines, which are catalogued in Table 111. Chemical shifts of the exocyclic carbons are shown in Chart I.