Tetrahedron Letters

Single-step synthesis of salans and substituted salans by Mannich condensation

EY Tshuva, N Gendeziuk, M Kol

文献索引：Tshuva, Edit Y; Gendeziuk, Natalie; Kol, Moshe Tetrahedron Letters, 2001 , vol. 42, # 36 p. 6405 - 6407

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被引用次数: 66

摘要

A convenient route for the synthesis of a variety of salan-type compounds is introduced. The synthesis is based on a single-step Mannich condensation between readily available starting materials: primary or secondary amines, formaldehyde and substituted phenols. This methodology is suitable for the preparation of chiral salans as well, which may find applications in asymmetric catalysis.