Aldolase-Catalyzed Synthesis of Conformationally Constrained Iminocyclitols: Preparation of Polyhydroxylated Benzopyrrolizidines and Cyclohexapyrrolizidines
... Volume: Page: ... Organic Letters. ... The rac-octahydroindole (5) (ie, with the proton at C2 in trans configuration with respect to the C3a and C7a protons) furnished three aldol adducts 16, 17a, and 17b (Scheme 2). Aldol adduct 16 could be separated, whereas 17a ...