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An Unusual dependency of counterion during wittig methylenation of bis-heteroaryl ketones

C Subramanyam

文献索引:Subramanyam, Chakrapani Tetrahedron Letters, 1995 , vol. 36, # 51 p. 9249 - 9252

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被引用次数: 10

摘要

Attempted Wittig methylenation of some bis-heteroaromatic ketones (8, 11 and 13) using MeP+ Ph3Br and n-BuLi gave none of the desired olefin. However, when KtBuO was used as the base for generation of the ylide, efficient olefination of these ketones was observed. A