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Reappraisal of Human CYP Isoforms Involved in ImipramineN-Demethylation and 2-Hydroxylation: A Study Using Microsomes Obtained from Putative Extensive and …

E Koyama, K Chiba, M Tani, T Ishizaki

文献索引:Journal of Pharmacology and Experimental Therapeutics, , vol. 281, # 3 p. 1199 - 1210

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被引用次数: 88

摘要

... of Japan, Tokyo (EK, TI), 2 Laboratory of Biochemical Pharmacology and Toxicology ... Consequently, we carefully reappraised the experimental conditions used for the previous in ... Experiments were performed with microsomal preparations obtained from the human livers of two ...