前往化源商城

1-Alkylamino-3-(2-thiazolyloxy)-2-propanols. Novel class of mixed myocardial. beta.-stimulants/. beta.-blockers

JA Edwards, B Berkoz, GS Lewis…

文献索引:Edwards,J.A. et al. Journal of Medicinal Chemistry, 1974 , vol. 17, p. 200 - 203

全文:HTML全文

被引用次数: 9

摘要

The synthesis of a series of l-alkylamino-3-(2-thiazolyloxy)-2-propanols is described. Several compounds in this series, eg,(f)-l-isopropylamino-3-(2-thiazolyloxy)-2-propanol, are selective myocardial p-stimulants with a prolonged duration of action. The structure-activity relationships of these compounds are described.