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Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors

M Ichikawa, A Yokomizo, M Itoh, K Sugita…

文献索引:Bioorganic and Medicinal Chemistry, , vol. 19, # 6 p. 1930 - 1949

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被引用次数: 14

摘要

... Bioorganic & Medicinal Chemistry. ... trend, statins have become increasingly recognized as an imperfect medicine for all types of hypercholesterolemia, and an alternative antihyperlipidemic agent which does not inhibit isoprenoid biosynthesis is desired in medical practice. ...