Tetrahedron

Straightforward microwave-assisted synthesis of 2-thiazolines using Lawesson's reagent under solvent-free conditions

JA Seijas, MP Vázquez-Tato, J Crecente-Campo

文献索引：Seijas, Julio A.; Vazquez-Tato, M. Pilar; Crecente-Campo, Jose Tetrahedron, 2008 , vol. 64, # 39 p. 9280 - 9285

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被引用次数: 26

摘要

2-Thiazolines are synthesized from carboxylic acids and 1, 2-aminoalcohols in the presence of Lawesson's reagent under solventless conditions. The developed method is valid for either substituted or unsubstituted aminoalcohols and a wide variety of aromatic, heteroaromatic and aliphatic carboxylic acids; thus it constitutes a general synthetic method for these kinds of compounds. The role of Lawesson's reagent is dual: to transform the 1, 2 ...