Two series of compounds that are structurally related to benzomorphans, derived by structural modification of arylpiperazines with high 5-HT1A affinity and moderate σ affinity, were prepared in order to increase σ affinity and selectivity. All new compounds are N- substituted-ω-(1, 2, 3, 4-tetrahydronaphthalen-1-yl)-or-ω-(1, 2-dihydronaphthalen-4-yl)-n- alkylamines with, in some cases, a methoxy group on the tetralin moiety. They were tested ...
![1-环己基-4-[3-(1,2,3,4-四氢-5-甲氧基-1-萘)丙基]-吡嗪结构式](https://image.chemsrc.com/caspic/280/172906-90-0.png)
