Synthesis of Casein-Related Peptides and Phosphopeptides. VIII. The Synthesis of Ser (P)-Containing Peptides by the Use of Z-Ser (PO3R2)-OH Derivatives
JW Perich, PF Alewood, RB Johns
文献索引：Perich, John W.; Alewood, Paul F.; Johns, R. B. Australian Journal of Chemistry, 1991 , vol. 44, # 2 p. 253 - 263
Abstract. The synthesis of five Z-Ser (PO 3 R 2)-OH (R= phenyl, ethyl, methyl, benzyl, t-butyl) derivatives is described by a simple three-step synthetic procedure which features the use of either (A) diphenyl or dialkyl phosphorochloridate/pyridine or (B) dialkyl N, N- diethylphosphoramidite/1H-tetrazole-m-chloroperoxybenzoic acid for the phosphorylation of the serine hydroxy group. The benzyl phosphate derivative, Z-Ser (PO 3 Bzl 2)-OH, was ...
