A novel series of p38 MAP kinase inhibitors for the potential treatment of rheumatoid arthritis

DS Brown, AJ Belfield, GR Brown, D Campbell…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 21 p. 5383 - 5387

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被引用次数: 30

摘要

... Bioorganic & Medicinal Chemistry Letters. ... The bisamides were prepared as exemplified by the synthesis of 18 in Scheme 1. The 3-morpholinobenzoic acid 31 was prepared either via palladium-catalysed amination chemistry from ethyl 3-bromobenzoate 19 or by direct ...