Acrylate as an Efficient Dimethylamine Trap for the Practical Synthesis of 1-tert-Butyl-4-piperidone via Transamination

JS Amato, JYL Chung, RJ Cvetovich…

文献索引：Tortolani, David R.; Poss, Michael A. Organic Letters, 1999 , vol. 1, # 8 p. 1261 - 1262

全文：HTML全文

被引用次数: 10

摘要

... Furthermore, hindered amines tended to produce bis-amine Michael adducts. figure ... Evaporation of the organic extracts afforded essentially pure 1 in 87% assay yield. ... Chim. Acta 1966, 49, 690−695. [CrossRef], [CAS] Synthesis of 4-chloropiperidines. Fankhauser, R.; Grob, CA ...