Synlett

Metallation versus heteroatom lithium complexation: Mono-and dilithiation of dipyridylpiperazines

F Louërat, PC Gros, Y Fort

文献索引：Louerat, Frederic; Gros, Philippe C.; Fort, Yves Synlett, 2006 , # 9 p. 1379 - 1383

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被引用次数: 10

摘要

Abstract BuLi-LiDMAE induced the efficient lithiation of dipyridylpiperazines despite strong competing lithium coordination by several nitrogen atoms. Symmetrical substrates led to a one-pot dilithiation while dissymmetrical species gave mono-or dilithiation under temperature control.