Drugs derived from cannabinoids. 5.. DELTA. 6a, 10a,-Tetrahydrocannabinol and heterocyclic analogs containing aromatic side chains

…, A Dren, D Dunnigan, R Hallas, K Hwang…

文献索引：Winn; Arendsen; Dodge; Dren; Dunnigan; Hallas; Hwang; Kyncl; Lee; Plotnikoff; Young; Zaugg Journal of Medicinal Chemistry, 1976 , vol. 19, # 4 p. 461 - 471

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被引用次数: 31

摘要

Ten new A h J h THC analogs with arylalkyl side chains, one with a dimethylaminoalkyl side chain, and six heterocyclic AGaJoa-THC analogs [8-substituted 5, 5-dimethyl-l0-hydroxy-2- (2-propynyl)-l, 2, 3, 4-tetrahydro-5~-[l] benzopyrano [4, 3-~] pyridines] were prepared. They showed pharmacological activity as analgesics, tranquilizers, antihypertensives, and hypnotics and as antisecretory, antiulcer, and antidiarrheal agents. The most potent ...