When enamine 1 was subjected to these conditions for 4 h, the aniline derivative 11 was isolated in 86% yield after purification by flash chromatography on silica gel (Table 1, entry 1). The aromatization reaction is general. A variety of morpholinoenamines, derived from substituted cyclohexanones such as 4-tert-butyl-, 2-methyl-, 3-methyl-, 3,5-dimethyl-, 2,3-dimethyl-, and 2-ethoxycarbonylcyclohexanone, were transformed to the corresponding substituted ...
