Tetrahedron

Carbocyclic 4′-epi-formycin

J Zhou, M Yang, A Akdag, H Wang, SW Schneller

文献索引：Zhou, Jian; Yang, Minmin; Akdag, Akin; Wang, Haisheng; Schneller, Stewart W. Tetrahedron, 2008 , vol. 64, # 2 p. 433 - 438

全文：HTML全文

被引用次数: 21

摘要

Formycin is a naturally occurring biologically responsive C-nucleoside. In pursuing the design and syntheses of novel C-nucleosides, convenient access to carbocyclic C- nucleosides based on the formycin framework was a goal. One such target was carbocyclic 4′-epi-formycin (4). This compound is reported via a procedure based on an asymmetric aldol/ring closure metathesis strategy. To provide a preliminary glimpse into the biological ...