Derivatives of side-chain hydroxylated nitrosamines Direct acting mutagens in Salmonella typhimurium

CJ Michejda, AW Andrews, SR Koepke

文献索引：Michejda,C.J. et al. Tetrahedron Letters, 1976 , p. 2573 - 2576

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被引用次数: 26

摘要

Abstract Methyl-(β-tosyloxyethyl) nitrosamine and 3-methyl-4, 5-dihydro-1, 2, 3-oxadiazolium tosylate are potent direct acting mutagens in the Ames assay, as is N-nitrosoprolinyl tosylate. These compounds are derived from β-hydroxylated nitrosamines. The closely related methyl-