Journal of Heterocyclic Chemistry

A synthetic entry into the 2??and 3??substituted??methyl 2, 3??dihydro??1, 4??benzoxazine series

GWH Potter, AM Monro

文献索引：Potter,G.W.H.; Monro,A.M. Journal of Heterocyclic Chemistry, 1972 , vol. 9, p. 299 - 301

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被引用次数: 5

摘要

Abstract Nmr spectroscopy has been used to demonstrate that the reported preparation of supposed 3-bromomethyl-2, 3-dihydro-1, 4-benzoxazine (3) is in error, the product of the reaction being in reality a monocyclic compound, 4. An alternative entry to the 3-substituted series is described in the synthesis of the 3-hydroxymethyl derivative, 10, the structure of which was established by nmr and mass spectroscopy. The previous assignment of ...