Medicinal Chemistry Research

Antibacterial activity of aminals and hemiaminals of pyrazole and imidazole

S Lupsor, F Aonofriesei, M Iovu

文献索引：Lupsor, Simona; Aonofriesei, Florin; Iovu, Mircea Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3035 - 3042,8

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被引用次数: 4

摘要

Abstract Antibacterial activity of 1, 1′-methylenedipyrazole (AM1), 1-hydroxymethylpyrazole (SAM1), 1, 1′-methylenediimidazole (AM2), and 1-hydroxymethylimidazole (SAM2) has been tested against reference and clinical strains by both difusimetric and broth dilution methods. Overall, the minimal inhibitory concentrations of tested compounds ranged from 180 to 270 μg/ml, while the minimal bactericidal concentrations were between 360 and ...