Synthesis of pyridinium amphiphiles used for transfection and some characteristics of amphiphile/DNA complex formation
…, P Haadsma, B Bosgraaf, MC Stuart, A Brisson…
文献索引：Meekel, Arthur A. P.; Wagenaar, Anno; Smisterova, Jarmila; Kroeze, Jessica E.; Haadsma, Peter; Bosgraaf, Bouke; Stuart, Marc C. A.; Brisson, Alain; Ruiters, Marcel H. J.; Hoekstra, Dick; Engberts, Jan B. F. N. European Journal of Organic Chemistry, 2000 , # 4 p. 665 - 673
Pyridinium amphiphiles have found practical use for the delivery of DNA into cells. Starting from 4-methylpyridine, a general synthesis has been devised for the production of pyridinium amphiphiles which allows variation in both the hydrophobic part and in the headgroup area of the compounds.
