Development of a fluorogenic probe with a transesterification switch for detection of histone deacetylase activity

R Baba, Y Hori, S Mizukami…

文献索引：Journal of the American Chemical Society, , vol. 134, # 35 p. 14310 - 14313

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被引用次数: 39

摘要

... While the acetamide of the acetyl-Lys is chemically inert, the primary amine generated by the HDAC reaction is highly nucleophilic and reacts with ... Corminboeuf, Clemence; Hu, Po; Tuckerman, Mark E.; Zhang, Yingkai. Journal of the American Chemical Society (2006), 128 (14 ...