Aryl–Aryl Bond Formation by the Fluoride??Free Cross??Coupling of Aryldisiloxanes with Aryl Bromides

CM Boehner, EC Frye, KMG O'Connell…

文献索引：Boehner, Christine M.; Frye, Elizabeth C.; O'Connell, Kieron M. G.; Galloway, Warren R. J. D.; Sore, Hannah F.; Dominguez, Patricia Garcia; Norton, David; Hulcoop, David G.; Owen, Martin; Turner, Gillian; Crawford, Claire; Horsley, Helen; Spring, David R. Chemistry - A European Journal, 2011 , vol. 17, # 47 p. 13230 - 13239

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被引用次数: 5

摘要

Abstract The prevalence of the biaryl structural motif in biologically interesting and synthetically important molecules has inspired considerable interest in the development of methods for aryl–aryl bond formation. Herein we describe a novel strategy for this process involving the fluoride-free, palladium-catalysed cross-coupling of readily accessible aryldisiloxanes and aryl bromides. Using a statistical-based optimisation process, ...