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Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1, 2, 4-triazol-5-ylmethoxy) pyrazolo [1, 5-d][1, 2, 4] triazine, a …

P Jones, JR Atack, MP Braun, BP Cato…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 4 p. 872 - 875

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被引用次数: 17

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Synthetic chemistry was then deployed to synthesise these compounds with a view to confirming the metabolic routes and ensuring the biological activity observed was not the result of an active metabolite. ...