Enantioselective conjugate addition of a lithium ester enolate catalyzed by chiral lithium amides

…, A Harrison-Marchand, J Maddaluno, K Tomioka

文献索引：Iguchi, Mayu; Tomioka, Kiyoshi Organic Letters, 2002 , vol. 4, # 24 p. 4329 - 4331

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被引用次数: 31

摘要

Mixed aggregates of chiral lithium amide and lithium ester enolate have been employed in the enantioselective conjugate addition on α, β-unsaturated esters. Michael adducts were obtained in ee's up to 76% combining a lithium enolate and a chiral 3-aminopyrrolidine