Gold Glyconanoparticles: Synthetic Polyvalent Ligands Mimicking Glycocalyx??Like Surfaces as Tools for Glycobiological Studies

…, TC Rojas, A Fernández, S Penadés

文献索引：Barrientos, Africa G.; De la Fuente, Jesus M.; Rojas, Teresa C.; Fernandez, Asuncion; Penades, Soledad Chemistry - A European Journal, 2003 , vol. 9, # 9 p. 1909 - 1921

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被引用次数: 252

摘要

Abstract A simple and versatile methodology is described for tailoring sugar-functionalised gold nanoclusters (glyconanoparticles) that have 3D polyvalent carbohydrate display and globular shapes. This methodology allows the preparation of glyconanoparticles with biologically significant oligosaccharides as well as with differing carbohydrate density. Fluorescent glyconanoparticles have been also prepared for labelling cells in biological ...