Inhibition of uridine phosphorylase: synthesis and structure-activity relationships of aryl-substituted 5-benzyluracils and 1-[(2-hydroxyethoxy) methyl]-5-benzyluracils.

GF Orr, DL Musso, GE Boswell, JL Kelley…

文献索引：Journal of Medicinal Chemistry, , vol. 38, # 19 p. 3850 - 3856

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被引用次数: 15

摘要

... The 2-thioxo-4-pyrimidinones 6 in Table 2 were prepared from the appropriate ethyl phenylpropionates 3 and 4 in two steps by method D or E. Method D, 0 1995 American Chemical Society Page 2. ... Journal of Medicinal Chemistry, 1995, Vol. 38, No. 19 3861 ...