Synthesis

Cross mannich reaction of aldehydes; efficient synthesis of substituted pyridines

A Winter, N Risch

文献索引：Winter, Andreas; Risch, Nikolaus Synthesis, 2003 , # 17 p. 2667 - 2670

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被引用次数: 23

摘要

Due to the diversity of applications and the broad distribution of pyridine derivatives in nature, numerous synthetic methods for these heterocyclic systems have been investigated. [1] Our studies in the field of ternary iminium salts led to the development of efficient one-pot reactions yielding a wide range of functionalized pyridines, bipyridines and terpyridines. [2] All these reactions are based on the ability of Mannich bases 1 to form α,β-unsaturated ...