Journal of Medicinal Chemistry

Derivatives of hydroxylamine: central nervous system stimulants

RT Major, KW Ohly

文献索引：Major,R.T.; Ohly,K.W. Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 4, p. 51 - 65

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被引用次数: 10

摘要

The value of the drug, iproniazid, I-isonicotinoyl-% isopropyl-hydrazine, in the treatment of certain types of apathy and depression has led to the study of a number of other derivatives of hydrazine for that purpose. 1-3 It was postulated that iproniazid owed its antidepressive properties to the fact that it is a monoamine oxidase inhibitor.* It has been found that most, if not all, of the new antidepressive hydrazine derivatives were monoamine oxidase ...