Synthesis of 15R-PGD 2: a potential DP 2 receptor agonist

S Kim, S Bellone, KM Maxey, WS Powell, GJ Lee…

文献索引：Kim, Seongjin; Bellone, Sophie; Maxey, Kirk M.; Powell, William S.; Lee, Gue-Jae; Rokach, Joshua Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1873 - 1876

全文：HTML全文

被引用次数: 14

摘要

The first total synthesis of 15R-PGD23 was accomplished. The approach used in this report is also an efficient method to produce 15R-PGE2. 15R-PGD2, a potential DP2 receptor agonist, could be an important novel tool for defining the role of this receptor in inflammatory diseases.