Synthesis, enzyme kinetics and computational evaluation of N-(β-D-glucopyranosyl) oxadiazolecarboxamides as glycogen phosphorylase inhibitors

M Polyák, G Varga, B Szilágyi, L Juhász…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 21, # 18 p. 5738 - 5747

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被引用次数: 3

摘要

... Bioorganic & Medicinal Chemistry. ... University of Debrecen, PO Box 20, H-4010 Debrecen, Hungary; b Department of Medical Chemistry, Medical and Health ... Bioisosteric replacement is widely used in medicinal chemistry to design new drug molecules by systematic modification ...