1, 2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents

JJ Li, GD Anderson, EG Burton…

文献索引：Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4570 - 4578

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被引用次数: 190

摘要

... 0022-262319511838-4570$09.00/0 0 1995 American Chemical Society Page 2. 2,2-Diarylcyclopentenes as COX-2 Inhibitors DuP 607 NS-308 ... 7g (COX-2, IC50 = 0.01 pM; COX-1, IC50 >lo0 /AM) Page 3. 4572 Journal of Medicinal Chemistry, 1995, Vol. 38, NO. 22 ...