Synthesis and reactivity of 3-R-1-adamantyl methyl ketones

VV Pozdnyakov, NV Makarova, IK Moiseev

文献索引：Pozdnyakov; Makarova; Moiseev Russian Journal of Organic Chemistry, 2001 , vol. 37, # 9 p. 1228 - 1231

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被引用次数: 3

摘要

Abstract A general procedure was proposed for synthesizing 3-R-1-adamantyl methyl ketones from the corresponding adamantanecarbonyl chlorides and dimethyl malonate in toluene (benzene) in the presence of sodium hydroxide. Intermediate dimethyl (3-R-1- adamantylcarbonyl) malonates can also be isolated. The resulting ketones were brought into reactions with hydroxylamine and formamide in the presence of formic acid to obtain ...