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Novel perfluoroalkylated oligo (oxyethylene) methyl ethers with high hemocompatibility and excellent co-emulsifying properties for potential biomedical uses

R Kaplánek, O Paleta, I Ferjentsiková…

文献索引:Kaplanek, Robert; Paleta, Oldrich; Ferjentsikova, Ivana; Kodicek, Milan Journal of Fluorine Chemistry, 2009 , vol. 130, # 3 p. 308 - 316

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被引用次数: 18

摘要

Two series of novel perfluoroalkylated amphiphilic compounds were synthesized from monomethyl ethers of mono-, di-and tri-(oxyethylene) glycols. The first series CH3 (OCH2CH2) nOCH2CH (OH) CH2–CF2 (CF2CF2) nCF3 (n= 1–3) bearing the hydroxy group at the spacer between hydrophilic and hydrophobic parts was prepared by the reactions of the monomethyl ethers with 2-(perfluoroalkylmethyl) oxiranes in 76–97% ...