Abstract Several monocarbamate compounds derived from felbamate were synthesized and 11 target compounds (1, 4, and 6–14) were initially evaluated in mice MES and PTZ models in our laboratory. Carbamate compounds with varying substituents on the oxygen (1–4) gave anticonvulsant activity with a wide range of ED 50 in MES test from< 20 mg/kg (2) to> 300 mg/kg (4) and compounds with different groups on the nitrogen (5–14) also were ...
