Synthesis

2-Substituted 4-(trifluoromethyl) phenols by directed ortho-lithiation

H Geneste, B Schäfer

文献索引：Synthesis, , # 15 p. 2259 - 2262

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被引用次数: 15

摘要

... Although usually rather low, the reactivity of the trifluoromethyl group is greatly enhanced in p-trifluoromethyl-substituted phenols. ... [8h] [15] Moreover, the ... and convenient method for the chlorination of 1b was the addition of hexachloroethane (entry 6). [16] For the synthesis of the ...