(2 E)-5-[3-[(Phenylsulfonyl) amino] phenyl]-pent-2-en-4-ynohydroxamic Acid and Its Derivatives as Novel and Potent Inhibitors of ras Transformation

M Ohtani, T Matsuura, K Shirahase…

文献索引：Journal of Medicinal Chemistry, , vol. 39, # 15 p. 2871 - 2873

全文：HTML全文

被引用次数: 17

摘要

... Journal of Medicinal Chemistry. ... activity with an MIC value of 17 μM. Chemistry. The target compounds were prepared using a straightforward process known in the literature. (6Z)- and (6E)-6-[2-[(phenylsulfonyl)amino ...