Syntheses of substituted 2??(l??methyl??2??imidazolyl) quinolines

M Khazan, F Hadizadeh…

文献索引：Khazan, Minoo; Hadizadeh, Farzin; Shafiee, Abbas Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 5 p. 1543 - 1547

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被引用次数: 2

摘要

Abstract Reaction of methyllithium with 1-methy1-2-imidazolecarboxaldehyde afforded the corresponding alcohol 2. Oxidation of compound 2 with manganese dioxide gave 2-acety1- 1-methylimidazole (3). Using compound 3 and substituted isatins 4, the corresponding quinoline-4-carboxylic acids (5) were prepared. The reaction of acid imidazolides of 5 with appropriate amines yielded the amides 6. Carbamic acid esters 10 were prepared by the ...