A method for the preparation of [13C6]??labelled 2??substituted naphthalenes

GJ Ellames, JM Herbert

文献索引：Ellames, George J.; Herbert, John M. Journal of Labelled Compounds and Radiopharmaceuticals, 2010 ,  vol. 53,  # 14  p. 801 - 803

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被引用次数: 3

摘要

Abstract A reliable route is described for the preparation of various 2-substituted derivatives of [1, 2, 3, 4, 4a, 8a-13 C 6]-naphthalene via the bromide 10. The approach is used to prepare [naphthalene-1, 2, 3, 4, 4a, 8a-13 C 6]-2-(2-bromoethyl) naphthalene (1), a key intermediate in the synthesis of labelled SR57746A, Xaliproden (2). Copyright© 2010 John Wiley & Sons, Ltd.