Chemistry Letters

Highly enantioselective aldol reaction of methyl ketones via chiral stannous azaenolates

K Narasaka, T Miwa, H Hayashi, M Ohta

文献索引：Narasaka, Koichi; Miwa, Tetsuo; Hayashi, Hiroki; Ohta, Masako Chemistry Letters, 1984 , p. 1399 - 1402

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被引用次数: 13

摘要

Chiral 1, 3-oxazolidines are readily prepared from methyl ketones and chiral norephedrine. Formation of stannous azaenolates from the oxazolidines and reaction with aldehydes followed by removal of the chiral auxiliary lead to the aldol products in high level of enantiomeric purity.