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Novel cyclopropapyrroloindole derivative (AT-3510) bearing methoxycarbonyl and trifluoromethyl groups

Y Fukuda, H Furuta, Y Kusama, H Ebisu…

文献索引:Fukuda, Yasumichi; Furuta, Hirosuke; Shiga, Futoshi; Asahina, Yoshikazu; Terashima, Shiro Heterocycles, 1997 ,  vol. 45,  # 12  p. 2303 - 2308

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被引用次数: 30

摘要

The seco-Cl 3-methoxycarbonyl-2-trifluoromethylcyclopropapyrroloindole (MCTFCPI) derivatives dl-and/or (S)-10 carrying various acyl moieties at the N6-position were synthesized along with their prodrugs (S)-12, and their antitumor activity was evaluated.