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Synthesis

Synthesis of 4, 4′-Disubstituted Azepines via Ring-Closing Metathesis Reaction and Asymmetric Arylation of Lactones

L Delhaye, A Merschaert, K Diker, IN Houpis

文献索引:Delhaye, Laurent; Merschaert, Alain; Diker, Khalid; Houpis, Ioannis N. Synthesis, 2006 ,  # 9  p. 1437 - 1442

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被引用次数: 11

摘要

Abstract The syntheses of the title compounds were accomplished via an original sequence of reactions including the ring-closing metathesis of ω-dienes by using the second- generation Grubbs' catalyst. The chiral diene precursors are available in racemic or optically enriched form from the corresponding α, α′-disubstituted lactones derivatives