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Synthesis

Synthesis of 2-alkyl-2-cyclopenten-1-ones. A versatile kinetic alkylation-ozonolysis procedure for the preparation of γ-ketoaldehydes

NWA Geraghty, NM Morris

文献索引:Geraghty, Niall W. A.; Morris, Noreen M. Synthesis, 1989 , # 8 p. 603 - 607

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被引用次数: 11

摘要

A range of 2-alkyl-2-cyclopentcn-1-ones including the pl '() Slilgl2ll'ldlI\ precursor 2-(6- mcth0xycarbonylhexyl)-2-cyclopenten-l-one and the jasmorioid precursor 2-[(Z)-2-pentenyl]- 2~ cyclopenten-1-one, have been prepared by a short synthetic route which begins with 6-- methyl-5-hcplen-2-one and generates the key 1, 4-ketoaldehyde intermediates by a kinetic alkylation--ozonolysis procedure.