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European journal of organic chemistry

Total Synthesis of (±)??Decursivine

AB Leduc, MA Kerr

文献索引:Leduc, Andrew B.; Kerr, Michael A. European Journal of Organic Chemistry, 2007 ,  # 2  p. 237 - 240

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被引用次数: 24

摘要

Abstract The first preparation of the antimalarial natural product decursivine is described. A Diels–Alder/Plieninger indolization protocol allows convenient preparation of the indole 15 which, in turn is a suitable substrate for a boron–enolate aldol reaction with piperonal (16). The resulting adduct 14 is transformed efficiently to the natural product.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)