Chemistry Letters

Novel synthesis and bridgehead functionalization of permethylbicyclo [2.2. 2] octasilane

W Setaka, N Hamada, M Kira

文献索引：Setaka, Wataru; Hamada, Natsuki; Kira, Mitsuo Chemistry Letters, 2004 , vol. 33, # 5 p. 626 - 627

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被引用次数: 14

摘要

Selective bridgehead chlorination of permethylbicyclo [2.2. 2] octasilane 1 giving the corresponding 1-chloro-(2a) and 1, 4-dichlorobicyclooctanes 3a was achieved using BCl 3 in chloroform. 1-Chlorobicyclooctane 2a resists the reactions with various nucleophiles such as phenyllithium and lithium aluminum hydride but reacts with KC 8 affording the corresponding silylpotassium 2b in quantitative yield.