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Tetrahedron

Efficient synthesis of 3-mono and disubstituted lactams using meerwein eschenmoser [3, 3] sigmatropic rearrangements.

B Coates, DJ Montgomery, PJ Stevenson

文献索引:Coates, Brian; Montgomery, David J.; Stevenson, Paul J. Tetrahedron, 1994 , vol. 50, # 13 p. 4025 - 4036

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被引用次数: 11

摘要

3-Allyl substituted five six and seven membered lactams, are readily available in good yields and reasonable selectivity by a formal Meerwein Eschenmoser [3, 3] rearrangement, using readily available methoxymethyleniminium salts and lithium alkoxides derived from allyl alcohols.