Monocharged inhibitors of mast cell tryptase derived from potent and selective dibasic inhibitors

JM Dener, VR Wang, KD Rice, AR Gangloff…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2325 - 2330

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被引用次数: 13

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Departments of Medicinal Chemistry, Biochemistry, and Enzymology, Axys Pharmaceuticals, Inc. ... Scheme 2 outlines the chemistry employed to prepare the piperazine-containing inhibitors of general structure Scheme 1 and Scheme 2 ...